"Explain me" or "explain to me"?
Can you explain me it?
Can you explain it to me?
The rule
You explain something TO someone. Say "explain it to me," not "explain me it."
"Explain" doesn't take a person as its direct object. You explain a thing, and if you mention the person, you add "to": explain something to someone.
This is different from "tell" and "give," which can take the person directly (tell me, give me).
More examples
She explained us the rules.
She explained the rules to us.
Please explain him this.
Please explain this to him.
How to remember it
explain / describe / suggest all need "to" before the person: explain it to me (not explain me).
Frequently asked
Why is "explain me" wrong?
Because explain is followed by the thing, not the person. Add "to" for the person: "explain it to me." Compare "tell me" (tell takes the person directly) with "explain it to me."
Which other verbs need "to"?
describe, suggest, mention, say, and recommend all take "to" before the person: "describe it to me," "suggest it to her."